Maternal hypothyroxinaemia during (early) gestation
نویسندگان
چکیده
منابع مشابه
Maternal circulating leukocytes display early chemotactic responsiveness during late gestation
BACKGROUND Parturition has been widely described as an immunological response; however, it is unknown how this is triggered. We hypothesized that an early event in parturition is an increased responsiveness of peripheral leukocytes to chemotactic stimuli expressed by reproductive tissues, and this precedes expression of tissue chemotactic activity, uterine activation and the systemic progestero...
متن کاملMaternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow-up study.
OBJECTIVE To evaluate the impact of maternal hypothyroxinaemia during early gestation (fT4 below the lowest tenth percentile and TSH within the reference range: 0.15-2.0 mIU/l) on infant development, together with any subsequent changes in fT4 during gestation. DESIGN A prospective 3-year follow-up study of pregnant women and their children up to the age of 2 years. MEASUREMENTS Child devel...
متن کاملMaternal selenium status during early gestation and risk for preterm birth.
BACKGROUND Preterm birth occurs in 5%-13% of pregnancies. It is a leading cause of perinatal mortality and morbidity and has adverse long-term consequences for the health of the child. Because of the role selenium plays in attenuating inflammation, and because low concentrations of selenium have been found in women with preeclampsia, we hypothesized that low maternal selenium status during earl...
متن کاملPremature brain aging in humans exposed to maternal nutrient restriction during early gestation.
BACKGROUND Prenatal exposure to undernutrition is widespread in both developing and industrialized countries, causing irreversible damage to the developing brain, resulting in altered brain structure and decreased cognitive function during adulthood. The Dutch famine in 1944/45 was a humanitarian disaster, now enabling studies of the effects of prenatal undernutrition during gestation on brain ...
متن کاملMaternal hypothyroxinaemia in pregnancy is associated with obesity and adverse maternal metabolic parameters.
OBJECTIVE Subclinical hypothyroidism and isolated hypothyroxinaemia in pregnancy have been associated with an increased risk of gestational diabetes. We aimed to ascertain if these women have a worse metabolic phenotype than euthyroid pregnant women. DESIGN, SUBJECTS AND METHODS We recruited 956 healthy Caucasian women with singleton, non-diabetic pregnancies from routine antenatal clinics. D...
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ژورنال
عنوان ژورنال: The Lancet
سال: 2005
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(05)66489-6